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It is not FDA approved in the US

Phenotypic variation and detection of carrier status in the partial androgen insensitivity syndrome

Kesarwani, K., Gupta, R., & Mukerjee, A

For example, active metabolites such as berberine and Astragaloside IV have been shown to alleviate glomerular and tubular damage by restoring the balance of the mTOR pathway and enhancing autophagic activity
