foxo4-dri peptide senolytic animal model 2023 Molecular modelling of the FOXO4-TP53 interaction to design peptides for the elimination of senescent cancer cells FOXO4-DRI alleviates RIPF. (A) Representative

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In 3-AR knockout mice, however, no effect was observed with AOD9604 confirming the dependency of its chronic lipolytic action on 3-AR expression, while also suggesting an additional acute mechanism that may operate through a separate pathway