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Orally administrated water-soluble CoQ10 enhanced bioavailability compared to lipid-soluble CoQ10 (Cui et al., 2021)

The sentence above, which is found in the primary article, would lead you to believe this, but if you dig through the 40-page supplementary information, you unearth this telling table: As you can see, the triglyceride, cholesterol, glucose and insulin levels of mice being fed normal chow are already pretty high (insulin levels at baseline convert to 16.3 microunits/ml)

The microarray results regarding the 28 NHRs is interesting because of three reasons: First, even considering the large number of NHR genes in worms (293), 9.6% is highly over-represented compared to other groups of genes with large numbers such as GPCR

While glucose, glutamine, and amino acids are well-recognized as critical energy sources and carbon donors during immune activation, the contribution of choline, a vitamin-like metabolite, has been overlooked