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Previous case reports regarding umbilical hernia were all with umbilical bulging, such as incarcerated umbilical Littre's hernia at the trocar site of a previous laparoscopic surgical procedure [7], sister Mary Joseph's nodule originating from endometrial carcinoma incidentally detected during surgery for an umbilical hernia [8], umbilical hernia masking primary umbilical endometriosis [9] and umbilical hernia with small bowel obstruction hidden within a chronic umbilical hernia sac in 45 years-old obese women with history of 5 years umbilical bulging [10]
Studies analyzing cytokines and chemokines in the plasma of patients with Wilson disease have enhanced our understanding of the underlying mechanisms and confirmed that the disease is driven by dysregulated inflammatory mediators [61,64,67]
Recent studies have highlighted the utility of biomarkers, such as NGF and BDNF, in predicting the progression of neuropathy and response to therapy
Dehydrated skin can delay healing and lead to uneven texture over time
