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Inconsistent Trial Results: While dementia trials show benefit, the CASTA stroke trial failure and Cochranes very low quality evidence rating raise questions about reproducibility

Bacteriostatic Water vs Sterile Water

Accordingly, inventors of the present invention have provided various embodiments showing at least 30 %, at least 50 %, at least 70 % and at least 90 % release over 24 hrs when tested in an In Vitro study using a Franz Diffusion Cell employing a dialysis membrane with l2-l4kd molecular weight cut off

Sustained receptor engagement allows continuous activation of satiety pathways without repeated peaks and troughs