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However folate stores are sufficient to last only a few months on a folate-free diet

Medication & Condition Review: Peptide therapy may not be appropriate for patients with certain medical conditions or those taking specific medications

While this explanation touches on some interesting concepts, there are several points that need clarification and might be oversimplified or speculative: Lets start with neuronal compensation

This hypothesis might have been corroborated by the observation that the levels of the cleaved forms of caspase-3 and PARP, both proteins which may be associated with programmed cell death, seemed to be reduced after introduction of AHK-Cu