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Sakurai M, Nakamura K, Miura K, Takamura T, Yoshita K, Morikawa Y, et al

Betaine was shown to suppress NLRP3 inflammasome activation and IL-1 production in the liver of diabetic mice by inhibiting insulin-induced activation of the FoxO1 transcription factor, leading to the activation of thioredoxin and hence suppression of ROS production in hepatocytes (Kim et al., 2017)

10.1016/j.bbrc.2015.12.124 Biochem

Contraindications Pregnant or nursing mares seek veterinary guidance before use
