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Other Double Agonists and Triple Agonist Beyond tirzepatide, pharmaceutical companies have developed additional dual receptor agonists targeting GLP-1 and glucagon (GCG) as well as triple receptor agonists.210 Mazdutide represents the most recent advancement in GLP-1/GCG dual receptor agonists;211213 this agent, co-developed by Cinda Biology and Lilly Pharmaceutical, received marketing approval in China on June 27, 2025

By mimicking the effects of the hormone GLP-1, Semaglutide helps regulate blood sugar levels, stimulates insulin secretion, reduces glucagon release, and slows gastric emptying

The companys email support may still take several days to a week to respond, but the chat function is top-shelf

How Semaglutide Works for Weight Loss Semaglutide functions as a GLP-1 receptor agonist, meaning it activates the glucagon-like peptide 1 receptor in the brain and gut