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Effects of Selenium Supplementation on Graves Disease: A Systematic Review and Meta-Analysis

Apparently trauma also can be a trigger

Beyond mitochondria, several intracellular enzymes contribute to the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS): NADPH oxidases, xanthine oxidoreductase, certain peroxisomal oxidases, cytochrome P450 enzymes, cyclooxygenases, and lipoxygenases
