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[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Gianaros P.J., Jennings J.R., Sheu L.K., Derbyshire S.W.G., Matthews K.A
Take, for example, CHK-cu, which is used for skin repair, wound healing, and collagen and hair follicle support
This suggests that immune dysregulation-induced gut microbiota dysbiosis and activation of the kynurenine pathway cause acute tryptophan depletion in the gut

Additionally, a decrease in the secretion of TNF-alpha was observed in primary fibroblasts