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Description
Such a process is described in Adenovirus infection

Biomolecules , 10 (10), 1429

(2019) 32:e12852

Humic acid can be biologically modified using specific microbes or enzymes to introduce or increase functional groups (e.g., carboxyl, hydroxyl), improve molecular complexity, and promote a more reactive structure, thereby enhancing its overall functionality and bioactivity [110]
