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ruthenicum on the myocardial lipid metabolism in rats with high-fat diet (Cui et al., 2020)
16,17 Accumulated toxic metabolites from compromised FAO (long-chain CoA-esters, or their free long-chain fatty acids) may cause adverse cellular effects because of altered pH (acid accumulation), inhibition of intermediary metabolism (acyl-CoA deficit), or cell damage due to free radical production
Results depend on model design, material handling, and validated research protocols
