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Description
Several animal studies indicate that MPs reduce gut microbial diversity and shift the dominant phylum ratioparticularly elevating the Firmicutes-to-Bacteroidetes (F/B) ratiowhile depleting beneficial genera like Bifidobacterium and enriching opportunistic pathogens like Staphylococcus 31,36,77
Of note, in initial [51,52,53,54,55] and later [56,57,58,59] eye studies, these points (i.e., pleiotropic cytoprotective beneficial effects of prostaglandins in glaucoma therapy) were not combined
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doi: 10.1158/0008-5472.CAN-10-1418
