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More interestingly, exogenous copper can promote ferroptotic cell death, but not Cuproptosis, by directly binding to GPX4 and further increasing GPX4 degradation [176]

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Great progress has been made in this field, but few natural product-based regimens have been recommended by clinical guidelines, and the mechanisms behind ethnomedicine are still not clearly explained

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Oxidative modification of lens crystallins by H 2 O 2 and chelated iron

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