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Gins et al., 2021)

Quantitative in vitro assessment of N-alkyl sulphate-induced cytotoxicity in human keratinocytes (HaCaT)

Clinical trials of folic acid supplementation in MS patients are also limited and showed improvement in Hcy levels, anemia, and quality of life of patients with relapsing-remitting MS with folic acid and vitamin B12 supplementation in one study [225] whereas no effect of folic acid supplementation was observed on disability of MS patients in another study [226]

Diagnosis of Laron syndrome therefore relies upon integration of clinical and biochemical findings and selecting patients for further genetic studies