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It was found that GHR expression and its protein level are reduced in the skeletal muscle of ATG7 knockout mice, implying a synchronous relationship between GHR and autophagy (Zecchini et al., 2019)

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A study showed that renal oxidative injury was aggravated and mitophagy was markedly decreased in aging HFD kidneys, whereas they were markedly ameliorated in kidneys upon dietary restriction [178]