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They have been widely used for NADs delivery due to their excellent compatibility with cell membranes

doi: 10.1080/15548627.2023.2218764 106 FlohLToppoSOrianL

However, it did not depend on NMDARs as it was not affected by the selective NMDAR-inhibitors ifenprodil or by 2R-amino-5-phosphonovalericacid (APV), indicating that [Thrombin] high -mediated LTP does not explain the acute effects of thrombin on seizure-induction (Maggio et al., 2008)
