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Ethics declarations Conflict of interest Song Mu, Claudia Andreu-Vieyra, Chester Lin, and Srikumar Sahasranaman are employees with stock grant or options in BeiGene

The harmful effect of ROS-induced tissue damage can be best alleviated by the following strategies

However, broader guidance from NICE, the NHS, and the MHRA provides a clear framework for understanding how unapproved substances should be approached
Other sweeteners have been linked to increased genotoxicity, cancer (Yilmaz & Ucar, 2014) insulin resistance, metabolic disease as well issues with gut bacteria and other negative side effects (Suez et al., 2014)
