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Before starting semaglutide, understanding what the medication can and cannot do helps set appropriate expectations
Excessive extracellular ROS/reactive nitrogen species initiates signalling cascades that lead to the onset of the inflammatory response, generating inflammatory mediators such as IL-1 , IL-6 and TNF- and activating NF- B signalling pathways (Reference Kaminska57Reference Kyriakis and Avruch60)
The prescriptions for tablets increased from half a million in 2015 to 2 million in 2024
Proc Natl Acad Sci 89:55825585
