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Although the exact mechanism of how this is achieved remains unknown, the authors emphasize the potential ability of GLP-1 to protect the central nervous system [57]

Vision Loss and NAION Concerns Non-arteritic anterior ischemic optic neuropathy (NAION) has emerged as a particularly devastating injury linked to GLP-1 medications, representing the second leading cause of optic nerve-related blindness in adults

The third trial involved only 82 patients and evaluated the effects of albiglutide versus placebo over a period of 12 weeks in individuals with HFrEF

Methods We searched PubMed for studies published before March 2025