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Deglutathionylation of 2-Cys peroxiredoxin is specifically catalyzed by sulfiredoxin
Ebselen also decreased 3-ntirotyrosine content in the lesions, as well as the expression of NOX2, and it altered the cellular composition of the lesions, decreasing the infiltration of macrophages
Thus, glutathione levels plays a critical role in these vitamins function
