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Description
Nausea from tirzepatide is mediated by GLP-1 receptor activation in the area postrema (brainstem vomiting center) and peaks 2472 hours post-injection, whereas 5-amino-1MQ has no known direct emetic mechanism

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Health Canada also warned about these risks, as well as the potential for mood swings, blood sugar imbalances, liver or kidney damage, and blood clots
