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& Kirschner, D

A way to reset the immune system Although CAR T-cell therapy is now generally considered safe, some patients have experienced difficult and serious side effects, such as neurologic toxicities or cytokine release syndrome, a condition where too many cytokines or proteins that regulate inflammation and immune response are released and result in a systemic inflammatory response in the body

The use of EVs as therapeutic targets or as drug carriers targeting novel inflammatory mediators may soon open new avenues for the clinical management of malignant diseases

Glutamate has been evaluated in a double-blinded RCT, showing that the selected dosage regimen was ineffective in the prevention of PIPN