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Current knowledge is largely derived from preclinical studies investigating the biological processes involved, with a lack of clinical trials confirming these effects in human subjects

The stained section samples were placed under an advanced positive fluorescence microscope (Axio Imager Z1, ZEISS) for observation, and a representative image of five fields per sample is shown

To study the mechanisms of nanocarrier uptake, hECs were pretreated with endocytosis inhibitor randomly methylated -cyclodextrin (CD