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In the spinal nerve ligation model, in which anatomic nerve regeneration can be easily observed, nicotine reduced anatomic measures of regeneration as well as expression of regeneration marker growth-associated protein 43 (GAP43)

Diltiazem may be useful (improve coronary vasoconstriction and hemodynamics)

There is also the need for higher level of care for larger animals, given their inherent longer life span, in turn, requiring more specialized care, both before and after trauma

First, the dose of 1.2 g/kg alcohol used in the avoid-explore tests did not increase locomotor activity, unlike a higher dose of 2 g/kg