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This heterotopic ossification is called Pelligrini-Stieda disease

(1) Mechanism of action: Pyridostigmine is a reversible acetylcholinesterase inhibitor that prevents acetylcholine (ACh) breakdown at the neuromuscular junction, thereby increasing neurotransmitter availability and enhancing neuromuscular transmission

While this effect has been primarily observed in the GI tract, there is evidence for similar benefit in cardiovascular, neurological, and muscle tissues, suggesting that BPC-157 may be used as both a therapy in the setting of stroke and heart attack as well as a probative peptide for understanding how to promote healing following ischemic injury [5], [6]

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