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In treating solid tumors, developing more tumor-targeting ASNase is one aspect, and the SLC1A3 inhibitor mentioned earlier also provides an idea to solve this problem

Purification and characterization of recombinant human interleukin-29 expressed in Escherichia coli
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4,26 PLP deficiency has also been reported to be caused by displacement of pyridoxal phosphate from circulating albumin by acetaldehyde (an alcohol metabolite), which increases urinary excretion
