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Receiver Operating Characteristic (ROC) analysis revealed that vanillic acid and N-hydroxy-isoleucine were the highest discriminative metabolites with an AUC value of 1 and also 2-aminobenzoic acid and picolinic acid showed high discriminative ability with an AUC of 0.995 and these might serve as potential prognostic biomarkers to monitor the progression of CKD to ESKD (Dahabiyeh et al., 2023)

The cell suspension was spun down at 14,000 g for 10 minutes, and 3 l of supernatant was applied to an Accucore 150 Amide HILIC HPLC column (100 2.1 mm, 2.6-m particle size) equipped with a guard cartridge (at 30 C)

10.1016/j.jconrel.2021.11.019 87 LiQ.ChenY.LiuH.TianY.YinG.XieQ

Dihexa initiates neuroplasticity that persists for weeks after the compound is undetectable in your system