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LAB utilise two primary pathways for lactose metabolism: the homofermentative pathway, resulting in the production of lactic acid, and the heterofermentative pathway, producing a combination of end products including carbon dioxide, ethanol, acetic acid, and lactic acid [177,178,179]

MUC15 degradation led to an increased proportion of T-ICs in HCC tissues, enhancing malignant proliferation and promoting lenvatinib resistance [158]

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We estimated a separate model for each feature