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Description
Sports Exercise 53 , 19871998 (2021)
Hanly M
22 To counteract these challenges, cells utilize molecular chaperones: proteins that assist in proper folding, prevent aggregation, refold misfolded proteins, and aid in protein transport and degradation, thereby maintaining proteostasis
Microglia: the metabolic checkpoint The decision of microglia to either support or prune neurons and synapses may be guided by a metabolic checkpoint. We postulate that microglia constantly assess the metabolic fitness of neighboring neurons by sensing specific metabolites released from dysfunctional cells
