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Tumor suppression and anticancer therapy Three peptides play an important role in the occurrence and development of tumors

Additionally, probiotics act on the surrounding environment and the host, enhancing host antioxidant activities, chelating metal ions, reducing activity of ROS-producing enzymes, and modulating key signaling pathways involved in oxidative stress such as Nrf2-Keap1-ARE, nuclear factor kappa-light-chain-enhancer of activated B cells, mitogen-activated protein kinase, and protein kinase C
however, the molecular mechanisms underlying this process remain unclear [323, 326] (Fig

Whilst the biological effect of IGF-1 is mediated by IGFRs, it is further affected by competitive action of other growth hormones
