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AKB-6548, a new hypoxia-inducible factor prolyl hydroxylase inhibitor increases hemoglobin while decreasing ferritin in a 28-day, phase 2a dose escalation study in stage 3 and 4 chronic kidney disease patients with anemia [Abstract]

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Nutritional supplementation with l-carnitine could mitigate these pathobiological processes by inhibiting NF-B and down-regulating NOX1/NOX2, thereby enhance the antioxidant effects of angiotensin II 636

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