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Antimalarials have a different mechanism of action than other immunomodulating therapies making them useful in combination therapy [42, 103105]

CD8 + T cells with or without ectopic expression of GPX4 were subsequently treated ex vivo in the presence or absence of A2ARi before being transferred into MC38-bearing mice

Domain I consists of a central four-stranded beta-sheet flanked on one side by two alpha-helices and on the other side by an irregular segment containing three short 3(10)-helices, while domain II is entirely helical

When nanomaterials are internalized by cells or tissues, they can elevate ROS levels, thereby decreasing cellular activity and inducing cytotoxicity [140, 155]