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Description
Meta-analysis of folic acid efficacy trials in stroke prevention: Insight into effect modifiers

It is not clear if or how much absorption occurs by the oral mucosa route owing to inadequate studies comparing sublingual with encapsulated B 12 .3,4 The sublingual formulations may achieve partial absorption directly through the oral mucosa, but it is conceivable that part of the B 12 may be bound by HC immediately in the saliva and then carried down to be absorbed in the GI tract by IF or by diffusion
Questions you may want to ask your doctor include: Does my risk of interactions depend on my dosage of Suboxone

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