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In addition, SCFAs can promote IL-22 production by type 3 innate lymphocytes (ILC3) and some CD4+ T cells through the expression of aromatic hydrocarbon receptors and hypoxia-inducible factor 1 (Yang et al., 2020)

The question remains could the TMAO be damaging the kidneys in the first place or is it just a sign of kidney damage

45 This method is the most applicable for widespread screening methods and has been implemented in newborn screening programs in developed nations
