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The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease
TP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution
In another research, the chitosan nanoparticles were exploited, because of their hydrophilic nature and cationic properties, which allowed them to cross the BBB and have a high drug entrapment and release efficiency (122)
Jiang et al., Itaconate attenuates osteoarthritis by inhibiting STING/NF-kappaB axis in chondrocytes and promoting M2 polarization in macrophages
