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The phase 2 and phase 3 trials focused primarily on total body weight reduction

Dysregulation of copper content can lead to the overproduction of ROS, which can act as a precursor to the development of neoplastic transformation and the formation of metastases [146,147]

Therefore, Shen et al attempted to coat alkaline chitosan on PLGA scaffolds in the expectation that chitosan would act as an acid neutralizer

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