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The mechanisms described above imply the activation of the signaling pathways characteristic for muscle metabolism: CPs raise the expression of the proteins: AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1) and phosphoinositide 3-kinase (PI3K) ( In addition, CPs might also influence the composition of gut microbiota, and correlation analyses suggest that there were up-regulated beneficial bacteria (such as Lactobacillus and Akkermansia ) upon supplementation with CP ( 4.5 Pea peptides: low allergenicity for special populations Pea peptides have lately become a good choice for those with certain diet restrictions mainly because they have low allergenicity (Figure 2)

Additional mechanisms of fatty acid metabolism that lead to interference in glucose uptake and utilization are the result of impaired insulin receptor signaling

10.1080/03639045.2019.1672717 Drug Dev Ind Pharm
