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Notably, the impact of H 2 O 2 /O/OH/ 1 O on the function of many proteins has been extensively reported, involving various molecular mechanisms over time [36, 101]

Nefrologia 40, 384394

Deficiencies in G6PD are the most commonly inherited enzyme deficiencies (enzymopathies) world wide with estimates of greater than 400 million affected individuals

This mechanism ensures that in the absence of oxidative stress or other stimuli, the expression of NRF2-dependent antioxidant genes is suppressed [88, 90]
