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Sanz-Cuesta T, Escortell-Mayor E, Cura-Gonzalez I et al (2020) Oral versus intramuscular administration of vitamin B12 for vitamin B12 deficiency in primary care: a pragmatic, randomized, non-inferiority clinical trial (OB12)

The more you drink, the more likely you are to suffer from it
Scientific factors affecting room temperature stability Multiple variables beyond temperature influence how long peptides remain viable at ambient conditions

As B12 is a water-soluble supplement, its safe to take at these higher doses
