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[132] [143] [153] Sufficiently overexpressing JunD in the nucleus accumbens with viral vectors can completely block many of the neural and behavioral alterations seen in chronic drug abuse (i.e., the alterations mediated by FosB)
further, patients who were involved in the study have received an unrefined form of the supplement
However, a study published in the Journal of the International Society of Sports Nutrition concluded that you do not have to load creatine
