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169,173 S100B is produced and secreted by astrocytes in the gray matter, 174 and changes in the levels of S100B in the blood and cerebrospinal fluid (CSF) of patients with MDD can cause glial cell dysfunction and damage

The mice were individually housed in standard polypropylene cages and kept under strictly controlled laboratory conditions (temperature: 22 2 C
These studies indicate that pharmacological inhibition of mAChRs modulates specific behavioral responses and further support these receptors as therapeutic targets for fragile X syndrome
(PubMed) Quadri P, Fragiacomo C, Pezzati R, et al
