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The majority of the aberrant metabolic effects of ethanol intoxication stem from the actions of ADH and ALDH and the resultant cellular imbalance in the NADH/NAD + ratio

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Nun estudo sobre a administracin oral intensa a grandes doses (3 gramos) de glutatin oral, Witschi e colaboradores concluron que "non posible incrementar o glutatin circulante ata un grao clinicamente beneficioso por medio da administracin oral dunha soa dose de 3 g de glutatin." [26] [27] O metabolito activo da vitamina D sintetizado nos riles calcitriol incrementa os niveis de glutatin no cerebro e parece ser un catalizador da producin de glutatin