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[DOI] [PMC free article] [PubMed] [Google Scholar] 341.Sun X
Interestingly, both in vivo and in vitro studies have shown that the accumulation of -syn in the mitochondria of human DA neurons leads to decreased complex I activity, increased production of ROS, reduced substrate-specific respiration, and increased mitophagy [86, 87]
[DOI] [PMC free article] [PubMed] [Google Scholar] Entezari M, Javdan M, Antoine DJ, Morrow DMP, Sitapara RA, Patel V, et al
Development and application of a comprehensive lipidomic analysis to investigate tripterygium wilfordii-induced liver injury
