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More specifically, researchers have observed that senescent cells resisted apoptosis due to elevated FOXO4 levels, which seem to regulate this process by interacting with p53

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Redox thresholds determine the responsiveness of the system, as the release is triggered when intracellular glutathione (GSH) levels surpass a specific threshold, typically elevated in cancer cells

doi: 10.1038/ki.2010.418 213
