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An early clinical trial in 13 patients with type 2 diabetes found that a single intravenous infusion of 1,000 mg of lipoic acid improved insulin-stimulated glucose disposal (i.e., insulin sensitivity) by 50% compared to a placebo infusion (57)

There is also an increased incidence in the Black population

A Quick Summary of Gut Health Care in Baltimore Leaky gut and gut dysfunction occur when the intestinal lining becomes permeable, letting food particles, toxins, and bacteria escape into the bloodstream and trigger chronic inflammation that fuels fatigue, brain fog, and skin issues

M.van der ValkM.van TellingenO.ReidG.et al (2002)