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Because of the structural diversity of natural fatty acids, many seemingly homologous enzymes are known for each step of the -oxidation cycle, including auxiliary enzymes for isomerase and reductase reactions together with acyl-CoA thioesterases, which remove any dead-end products

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It applies to clinical trials that use different extraction forms, for example, curcumin-containing substances with unspecified amounts of curcuminoids that prevent establishing the equivalency of doses or the minimum therapeutic threshold Large, more centralized, and strictly controlled clinical trials are required in the future to provide more scientific evidence to assess conferred benefit and a more secure way for adding these natural supplements to evidence-based treatment options for breast cancer