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According to a patent application by GW Pharmaceuticals, the makers of Epidiolex (a sublingual spray containing 100 mg of CBD/100 ml of solution), CBDA displays greater bioavailability and potency in treating epilepsy (GW PHARMA LTD, 2015)

As a result, pain is also highly associated with psychiatric comorbidities resulting in more severe pain, worse functioning and disability, lower quality-of-life, and higher incidences of opioid-use disorder [21]
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