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Description
Structurally, both PROTACs 81 and 82 present lenalidomide as a cereblon recruiting moiety linked to the linker via an amide bond 137,138

Antioxid Redox Signal (2011) 14(3):391401

Instead, HFD-fed Ssu72 aKO mice exhibited improved glucose tolerance and insulin sensitivity, along with reduced circulating free fatty acids and triglycerides

They found that Gln 2-substitution was the determinant of ASCT2 activity across all positional substitutions
