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Depending on the presence of specific features, they can be tissue- and/or disease-specific and may be detected in body fluids, thus making them highly attractive therapeutic targets and potential biomarkers 21

NAC and Selenium are two powerhouses when it comes to antioxidants

doi: 10.1016/j.bone.2014.07.006 57 CoaccioliSSarzi-PuttiniPZisPRinonapoliGVarrassiG

Notably, pro-inflammatory genes such as Il13, Il5, Csf2 among others were consistently downregulated following melatonin treatment ( Figure 5C )
